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Reference Guide
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3X4 Genetics
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3X4 Genetics Test + Blueprint Report

3X4 Genetics Test + Blueprint Report

By 
3X4 Genetics
3X4 Genetics Test + Blueprint Report
3X4 Genetics
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About the Test

The 3X4 Genetics Test + Blueprint Report from 3X4 Genetics is a comprehensive genetic analysis tool that delves into 36 pathways important in human health. By examining over 134 genes from a simple cheek swab, this test provides personalized insights into nutrition, fitness, illness prevention, weight management, stress reduction and health optimization strategies, and more.

Tailored recommendations offered through the Blueprint Report empower individuals to make informed decisions about their health and wellness based on their genetic makeup. This approach allows patients to gain a deeper understanding of how their genetics influence their health and enables them to take proactive measures to prevent illness, delay disease onset, and optimize overall well-being.  The test results are meant to be interpreted by the ordering healthcare provider within the context of an individual’s unique health history, lifestyle, goals and needs.

The 3X4 Genetics Test + Blueprint Report is ideal for individuals seeking a better understanding of their genetic predispositions and how they may impact health outcomes. By analyzing genetic markers related to various health parameters, this test equips patients with valuable insights to guide lifestyle choices, dietary habits, and personalized interventions to support their unique genetic profile. The test requires only a simple cheek swab sample, making it convenient and accessible for patients seeking personalized health insights at the cellular level.

How Does the 3X4 Genetics Test + Blueprint Report from 3X4 Genetics Present Test Results?

To maximize clarity for the individual and the provider, test results are organized and presented in four sections inside a comprehensive report: 

Your Summary Plan 

Your Summary Plan introduces the 3 most potentially relevant pathways to make changes for the most significant health improvements, based on the individual’s unique genetic results.  Within each pathway three suggested lifestyle interventions and three suggested supplements are offered to guide those changes.  

These suggestions are intended to be considered within the full context of an individual’s health history.  

Your Gene Results

The 3X4 Genetics test + Blueprint Report analyzes over 134 genes and organizes the information according to the gene’s potential effects in a particular biological pathway.  An individual’s unique genetic results are organized to promote easy implementation of results, from which genes demonstrated the highest impact on overall health, to those genes which demonstrated the lowest impact.  Overall, this section highlights an individual’s unique genetic potential and guides direction on how to optimize genetic expression for health.  

This section continues by demonstrating results according to the following systems, again highlighting those pathways that have the highest potential to impact a person’s health:

Cellular Health (Inflammation, Methylation, Oxidative Stress, Detoxification)

Systems (Mood and Behavior, Hormone Balance, Memory and Brain Health, Collagen and Joints, Bone Health, Histamine Overload, Glucose and Insulin)

Cardiovascular Health (Blood Pressure, Vascular Health, Cholesterol, Blood Clotting)

Energy (Exercise Response, Appetite/Satiety/Intake; Pro-inflammatory Fat, Adipogenesis, Energy Expenditure, Weight Gain and Weight Loss Resistance)

Activity (Training Response, Injury, Power, Recovery, Endurance)

Nutrients (Vitamin B12, Folate, Fatty Acids, Choline, Vitamin D, GLuten, Iron Overload, VItamin C, Caffeine, Salt)

Your Story

This section organizes an individual’s results as illustrations to tell the story of their unique genetic potential and emphasize significant pathways and potential interventions that may best support those pathways.  

Glossary and Detailed Results

This section contains a list of terms that may be helpful in clarifying test results.  It also includes a chart of the specific genes involved in each pathway contained in the test.  

Who Can Benefit from the Information Provided Inside the 3X4 Genetics Test + Blueprint Report By 3X4 Genetics?

The 3X4 Genetics Test + Blueprint Report By 3X4 Genetics provides information that may benefit many groups of people, including: 

Health-Conscious Individuals: those people interested in optimizing their lifestyle choices based on their genetic makeup.

Individuals Interested in Improving Athletic Performance and/or Supporting Weight Loss: this test can inform an individual’s exercise and diet plans to support optimal athletic performance and metabolism.  

Individuals Proactive About Disease Prevention and Management: this test may uncover an individual’s unique genetic tendencies and highlight important pathways that, when supported, improve overall health and wellness.  This may be particularly interesting to those with a family history of certain health conditions.

Those Seeking Personalized Strategies: whether for nutrition, fitness, weight management, or overall well-being, utilizing genetic information can provide highly individualized information to guide wellness or treatment decisions.   

Patients Seeking Greater Insight: those people looking to understand how their genetics can influence their health outcomes and make informed decisions accordingly may find many insights in the 3X4 Genetics Test + Blueprint Report.  

Collection and Shipping Instructions:

Key Details:

Avoid wearing lip balm and lipstick on the day of collection.

Certain activities should be avoided for 1 hour before sample collection.

Online test registration is mandatory to avoid additional fees; click here to register.  

For more information on how to register your test, click here.

Samples should be shipped via FedEx promptly after collection.

Preparation & Timing:

Refrain from wearing lip balm and lipstick.

Avoid eating, smoking, chewing gum, and drinking anything except water for 1 hour before collection.

Refrain from drinking water for 30 minutes before sample collection.

Collection Instructions:

Complete online test registration before sample collection.

Wash hands and write date of birth on the vial.

Place the vial upright on a flat surface.

Open the vial.  DO NOT touch or discard the liquid.

Unwrap the swab.  DO NOT touch the cotton end that will go in your mouth.

Using a lot of pressure, rub swab against the inside of both cheeks for 60 seconds each, rotating the tip as you swab.  .

Pick up the vial.  Slowly insert and twist the swab into the vial, using a corkscrew motion.

Move the swab rapidly up and down 10-15 times inside the tube, keeping the swab in the liquid the entire time.

Using a corkscrew motion, slowly twist the swab to remove it from the vial.  Seal vial tightly and take a picture of the kit code number or the QR code.

Place the vial in the provided ziplock bag and packaging tube.  Discard the swab.  

Requisition & Payment:

The kit is prepaid; no additional payment is required.

Online test registration is mandatory to avoid additional fees; click here to register.

For more information on registering your test kit online, click here.

Shipping:

Ensure online test registration is completed.

Place the sample vial in the ziplock bag, then into the packaging tube.

Seal the return mailer and note the tracking number for shipment via FedEx.

Results:

Results are typically released to the provider 28 business days after sample receipt at the lab, though processing time cannot be guaranteed.

Additional Resources for Practitioners:

References: 

Direct-to-Consumer Genetic Testing FAQ for Healthcare Professionals. Genome.gov. https://www.genome.gov/For-Health-Professionals/Provider-Genomics-Education-Resources/Healthcare-Provider-Direct-to-Consumer-Genetic-Testing-FAQ

Oh B. Direct-to-consumer genetic testing: advantages and pitfalls. Genomics Inform. 2019 Sep;17(3):e33. doi: 10.5808/GI.2019.17.3.e33. Epub 2019 Sep 26. PMID: 31610629; PMCID: PMC6808639.

About the Test

The 3X4 Genetics Test + Blueprint Report provides 36 key insights and practical, personalized recommendations for patients to start taking control of their health.

More Resources

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Biomarkers

SHBG gene
SHBG gene
BDNF gene
BDNF gene
MTHFR
MTHFR
MTR
MTR
MTRR
MTRR
COMT
COMT
FTO
FTO
MC4R
MC4R
GC
GC
SLC23A1
SLC23A1
FUT2
FUT2
NBPF3
NBPF3
PEMT
PEMT
FADS1
FADS1
FADS2
FADS2
HFE
HFE
GPX1
GPX1
ADIPOQ
ADIPOQ
TNF
TNF
PON1
PON1
HNMT
HNMT
ACE Gene
ACE Gene
CYP1A2
CYP1A2
NOS3
NOS3
GSTM1
GSTM1
VDR
VDR
CBS
CBS
CYP2R1
CYP2R1
APOA5
APOA5
DIO2
DIO2
GSTP1
GSTP1
BHMT
BHMT
MTHFD1
MTHFD1
CETP
CETP
CYP1B1
CYP1B1
CYP2C19
CYP2C19
UCP2
UCP2
UCP3
UCP3
ACSL1
ACSL1
ADRB3
ADRB3
AKT1
AKT1
ALDH2
ALDH2
ANK3
ANK3
APOA2
APOA2
APOC3
APOC3
CLOCK
CLOCK
COL3A1
COL3A1
CYP1A1
CYP1A1
CYP2C9
CYP2C9
CYP3A4
CYP3A4
DRD1
DRD1
DRD2
DRD2
DRD3
DRD3
F2
F2
F5
F5
FAAH
FAAH
FOXO1
FOXO1
FOXO3
FOXO3
GABRA2
GABRA2
GSTO2
GSTO2
HLA
HLA
ITGB3
ITGB3
MMP2
MMP2
MMP3
MMP3
NAT1
NAT1
NAT2
NAT2
NQO1
NQO1
OGG1
OGG1
PPARD
PPARD
SLC2A2
SLC2A2
SLCO1B1
SLCO1B1
SRD5A1
SRD5A1
UGT2B15
UGT2B15
UGT2B17
UGT2B17
VEGFA
VEGFA
ACTN3
ACTN3
ACVR1B
ACVR1B
AGT
AGT
CACNA1C
CACNA1C
COL1A1
COL1A1
CYP17A1
CYP17A1
CYP19A1
CYP19A1
EPHX1
EPHX1
FABP2
FABP2
GDF5
GDF5
IRS1
IRS1
MMP1
MMP1
OXTR
OXTR
PPARG
PPARG
TCF7L2
TCF7L2
UCP1
UCP1
ACE2
ACE2
CHRNA5
CHRNA5
CYP2D6
CYP2D6
LEPR
LEPR
PPARA
PPARA
SIRT1
SIRT1
TAS2R38
TAS2R38
TIMP4
TIMP4
ADRB2
ADRB2
AMPD1
AMPD1
CKM
CKM
COL12A1
COL12A1
CRP Gene
CRP Gene
DRD4
DRD4
HIF1A
HIF1A
HO-1
HO-1
HTR1A
HTR1A
LPL
LPL
SULT1A1
SULT1A1
APOE
APOE
GSTT1
GSTT1
IL1
IL1
PPARGC1A
PPARGC1A
TCN2
TCN2
SOD2
SOD2
OPRM1
OPRM1
IL6R
IL6R
DAO gene
DAO gene
IL6
IL6
PLIN1
PLIN1
NFE2L2
NFE2L2
CAT gene
CAT gene

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Lab Test Information
Price
$
299
.00
 $
299.00
Sign up to View
Lab Company
3X4 Genetics
Sample Type
Swab
Category
Shipping Time
2 - 4 days
FedEx
Turnaround Time
28 days
Test Preparation Starts
Up to 1 hours before collection
Number of Collection Days
1 day
Methods Used For Processing
DNA Microarray
Lab Certifications
CLIA Certified
CAP Accredited
ISO 15189
COLA Accredited
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