This panel uses a comprehensive method using ELISA methodology for detecting active and chronic Lyme disease, which may result in Lyme arthritis and neuroborreliosis.
It measures antibodies against the spirochete and various components of B. Burgdorferi, its subspecies, and co-infections.
ISL uses both Borrelia antigens grown in culture and the various proteins expressed in vivo, enabling us to improve the accuracy of our determinations.
In this patented ELISA methodology, we measure IgG and IgM antibodies not only against a mixture of Borrelia antigens but also against proteins or peptides of different molecular sizes, such as Outer Surface Protein A (OspA), Outer Surface Protein B (OspB), Outer Surface Protein C (OspC), Outer Surface Protein E (OspE), Leukocyte Function Associated Antigen (LFA), Variable Major Protein (VMP), and more, each component determined separately.
We also measure antibodies against antigens known for their involvement with Lyme disease, including antibodies against the Borrelia subspecies Sensu stricto, Afzelii, Garinii, and Myamotoi, as well as the co-infections Babesia, Bartonella and Ehrlichia.
It is vital to correctly determine as early as possible whether someone is developing Lyme disease or something else. False positive test results could lead to years of incorrect treatment and unnecessary medications with their side effects, while false negative results could lead to Lyme arthritis, neuroborreliosis, and years or even a lifetime of suffering.
This panel is beneficial for a wide variety of patients with the following:
symptoms and conditions, which are represented in the figure below:
Lyme borreliosis in humans is an inflammatory disease affecting multiple organ systems, including the nervous system, cardiovascular system, joints, and muscles.
This panel uses Immunosciences Lab's patented ELISA methodology to measure 26 different antibodies against Lyme-specific antigens, Borrelia subspecies, and co-infections. It can detect active and chronic Lyme disease, including Lyme arthritis and neuroborreliosis that may be confused with multiple sclerosis.