Add-On: Campylobacter

This is a single-marker test measuring Campylobacter. It is available only as an add-on to the GI Effects® profiles.

What is the Add-On: Campylobacter By Genova Diagnostics?

This test is an add-on to the full GI Effects profile.  This add-on test specifically looks for the presence of Campylobacter in the stool.  

Why is the Add-On: Campylobacter Clinically Relevant?

Campylobacter is a gram-negative food-borne bacterial pathogen; it is the most common food-borne pathogen in the US.  [4.]  Typical sources of infection include raw or undercooked foods, contaminated water and produce, untreated water and unpasteurized dairy products.  

Individuals infected with Campylobacter typically exhibit symptoms including diarrhea (frequently bloody), fever, and stomach cramps, often accompanied by nausea and vomiting. Onset of symptoms usually occurs between two to five days post-infection, lasting approximately one week. Complications may arise, such as irritable bowel syndrome, temporary paralysis, and arthritis. In individuals with weakened immune systems, such as those with blood disorders, AIDS, or undergoing chemotherapy, Campylobacter can occasionally disseminate to the bloodstream, leading to a potentially life-threatening infection. [1.]

It is not uncommon to recover without treatment, but some people will develop a chronic Campylobacter infection. [2.]  These individuals may have chronic diarrhea, or be asymptomatic. [2.]

Who Can Benefit From the Add-On: Campylobacter by Genova Diagnostics?

The Add-On: Campylobacter marker for the GI Effects profile by Genova Diagnostics is beneficial for anyone with chronic digestive symptoms, especially chronic diarrhea, for which no other cause can be found.

Collection and Shipping 

This test is an add-on, and it will be assessed in the sample provided by the patient for the full GI Effects profile.  Click here for Collection and Shipping Instructions.  

Additional Resources for Practitioners

Video: Interpreting the GI Effects Profile

Article: Using the GI Effects Test in Clinic

References

[1.] CDC. Questions and Answers . CDC. Published 2019. https://www.cdc.gov/campylobacter/faq.html ‌

[2.] Bloomfield SJ, Midwinter AC, Biggs PJ, et al. Long-term Colonization by Campylobacter jejuni Within a Human Host: Evolution, Antimicrobial Resistance, and Adaptation. The Journal of Infectious Diseases. 2017;217(1):103-111. doi:https://doi.org/10.1093/infdis/jix561

[3.] Fischer GH, Hashmi MF, Paterek E. Campylobacter Infection. [Updated 2024 Jan 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK537033/

[4.] Ford L, Healy JM, Cui Z, et al. Epidemiology and Antimicrobial Resistance of Campylobacter Infections in the United States, 2005–2018. Open Forum Infectious Diseases. 2023;10(8). doi:https://doi.org/10.1093/ofid/ofad378