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Reference Guide
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SDMA
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Symmetric Dimethylarginine

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What's 
SDMA
?
Symmetric Dimethylarginine (SDMA) is a natural substance that our bodies create when breaking down proteins. Recently, medical experts have started to pay more attention to SDMA because it can help us understand how well our kidneys are working. Unlike other indicators, SDMA levels in our blood can show early signs of changes in kidney function, often before we notice any symptoms. This is because our kidneys are responsible for removing almost all of the SDMA from our bodies, making it a reliable way to measure their performance. In short, SDMA is a useful tool for keeping an eye on our kidney health and making sure they continue to effectively clean waste from our blood.
If Your Levels Are High
Elevated SDMA levels might mean that your kidneys aren't working as well as they should. This could be due to a number of reasons, such as getting older, having high blood pressure, or taking certain medications that can affect how your kidneys work. Lifestyle factors, like eating a lot of protein, could also play a role, since your body makes more SDMA when it breaks down proteins. Long-term health issues like diabetes or high blood pressure might be involved too, as they can harm your kidneys over time. Keep in mind that while high SDMA levels can give an early warning of changes in kidney function, it doesn't always mean there's a major issue.
Symptoms of High Levels
Symptoms of high levels of SDMA may not be immediately noticeable, as changes in kidney function can often occur without causing any obvious signs. However, as kidney function continues to decline, you might experience fatigue, loss of appetite, nausea, or changes in urine output.
If Your Levels are Low
If your SDMA levels are lower than usual, it might mean that your kidneys are doing a great job at filtering waste from your blood. This could be because you're eating a lot of protein, which leads to more SDMA production, or because you're taking certain medications that help your kidneys work better. On the other hand, it's possible that your body isn't making enough SDMA, which could be due to not eating enough protein or having some issues with how your body processes protein. While low SDMA levels usually aren't a big worry, it's a good idea to keep an eye on them to make sure they stay within a healthy range.
Symptoms of Low Levels
Symptoms of low levels of SDMA are typically not noticeable, as this condition often doesn't present any specific signs.

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Symmetric Dimethylarginine

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