Anti-Scl-70

Scleroderma Antibody

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What's

Anti-Scl-70

Anti-Scl-70, also known as the Scleroderma Antibody, is a specific kind of autoantibody. An autoantibody is an immune protein that your body mistakenly creates to attack its own tissues. This particular autoantibody targets a protein called topoisomerase I, which is found in the center of your cells. The presence of Anti-Scl-70 in your blood is often linked to a rare autoimmune disorder called systemic scleroderma. This condition causes the skin and connective tissues to become hard and tight. It's important to note that Anti-Scl-70 doesn't cause the condition, but it's a marker that can be found in the blood when the condition is present.

If Your Levels Are High

Elevated levels of Anti-Scl-70 might mean that your body's defense system is reacting to something unusual happening inside you. This could be because your body is accidentally attacking its own tissues, which is known as an autoimmune reaction. Sometimes, certain medications or environmental factors can also trigger this response. High levels of Anti-Scl-70 are often associated with a condition called systemic scleroderma, which affects your skin and the tissues that connect your body parts. Keep in mind that Anti-Scl-70 doesn't cause this condition, but it's a sign that can be found in your blood when the condition is present.

Symptoms of High Levels

Symptoms of high levels of Anti-Scl-70 may not be directly noticeable as they are more associated with the underlying condition, such as systemic scleroderma. These can include skin hardening and tightening, joint pain, and in severe cases, dysfunction of organs such as the heart, lungs, or kidneys.

If Your Levels are Low

Having low levels of Anti-Scl-70 in your blood might mean that your body isn't producing a lot of this specific autoantibody. This could be due to various reasons, such as your body's natural immune response, the presence of other autoimmune conditions, or the effects of certain medications that impact your immune system. It's also possible that your body is doing a good job at managing its autoimmune response, which keeps the production of Anti-Scl-70 under control. However, it's important to remember that Anti-Scl-70 is just one part of the bigger picture and doesn't give a complete understanding of your overall health.

Symptoms of Low Levels

Symptoms of low levels of Anti-Scl-70 are typically absent, as this condition is often asymptomatic. This means that you may not experience any noticeable changes or discomfort.

See References

Test for

Scleroderma Antibody

AutoImmune Analyzer

Access Med Labs

Serum

This test measures antinuclear antibodies and other related markers to help diagnose autoimmune disease. Antinuclear antibodies are present in systemic lupus erythematosus, Sjogren’s Syndrome, scleroderma, mixed connective tissue disease, drug-induced lupus, and rheumatoid arthritis.

ANA Screen + 11 ANA Components

Access Med Labs

Serum

The ANA Screen detects the presence of clinically relevant circulating autoantibodies in serum. Antinuclear antibodies are present in systemic lupus erythematosus, Sjogren’s Syndrome, scleroderma, mixed connective tissue disease, drug induced lupus, and rheumatoid arthritis.

ANA 11 Components (no ANA Screen)

Access Med Labs

Serum

This test measures 11 antinuclear antibodies to help diagnose autoimmune disease. Antinuclear antibodies are present in systemic lupus erythematosus, Sjogren’s Syndrome, scleroderma, mixed connective tissue disease, drug-induced lupus, and rheumatoid arthritis.

Scl-70 Antibody

Access Labcorp Draw

Serum

This is a single-marker test measuring anti-Scl-70 antibodies. It is used to help diagnose scleroderma.

Scl-70 Abs

Access Med Labs

Serum

This is a single-marker test measuring anti-Scl-70 antibodies. It is used to help diagnose scleroderma.

CONTENTS

What is it?

High Levels

Low Levels

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