Immunoglobulin G1

High levels of Immunoglobulin G1 (IgG1) in your blood could suggest that your body is actively fighting off an infection or disease. This could be a bacterial or viral infection, or it could be an autoimmune disease, where your immune system mistakenly attacks your own cells. Certain medications, such as immunosuppressants, can also cause high IgG1 levels. In some cases, high levels might indicate a condition called IgG1 monoclonal gammopathy, which can be associated with diseases like multiple myeloma or lymphoma. It's also possible that an allergic reaction is causing the elevated IgG1 levels, as your body produces more of these proteins in response to allergens. Lastly, high IgG1 levels could be a sign of a chronic inflammatory condition, such as rheumatoid arthritis or lupus.

Symptoms of high levels of IgG1 could include fatigue, fever, joint pain, and swelling. In some cases, there might be no noticeable symptoms at all.

Low levels of Immunoglobulin G1 (IgG1) in your blood could suggest that your body's defense system isn't producing enough 'soldiers' to fight off infections. This could be due to a variety of reasons. For instance, you might have an immune system disorder, such as Common Variable Immunodeficiency (CVID) or Selective IgG Subclass Deficiency, which can affect your body's ability to produce IgG1. Certain medications, like immunosuppressants or chemotherapy drugs, can also lower your IgG1 levels. Additionally, malnutrition or a protein-losing condition, like kidney disease or severe burns, could be factors. It's important to note that low IgG1 levels don't always mean there's a problem, as some healthy individuals naturally have lower levels.

Symptoms of low levels of Immunoglobulin G1 could include frequent or recurrent infections, such as sinus infections, lung infections, or ear infections. You might also experience gastrointestinal issues, like diarrhea or weight loss. In some cases, individuals with low IgG1 levels may not show any symptoms at all.