E3/(E1+E2)

A high E3/(E1+E2) ratio indicates that there is more estriol (E3) in your body compared to estrone (E1) and estradiol (E2). This could be due to a variety of reasons. For instance, it could suggest that you are pregnant, as estriol levels typically surge during pregnancy. Alternatively, it could be a sign that your body is producing more E3 for other reasons, such as in response to certain medications like oral contraceptives or hormone replacement therapy, which can alter estrogen levels. It could also indicate a hormonal imbalance, possibly due to conditions like polycystic ovary syndrome (PCOS) or ovarian tumors, which can affect the production of different forms of estrogen. However, it's important to note that a high E3/(E1+E2) ratio is just one piece of the puzzle and should be considered in the context of other diagnostic information.

Symptoms of high levels of E3/(E1+E2) could include changes in menstrual cycle, mood swings, bloating, and tenderness in the breasts. However, it's also possible to have a high E3/(E1+E2) ratio without experiencing any noticeable symptoms.

A low E3/(E1+E2) ratio means that your body has less estriol (E3) compared to the combined levels of estrone (E1) and estradiol (E2). This could be due to various reasons. For instance, if you're not pregnant, it's normal to have lower levels of E3, as this form of estrogen is mainly produced during pregnancy. However, if you're of reproductive age and not menopausal, a low ratio could indicate that your body is producing more of the potent E2 estrogen, which could be due to factors like stress, obesity, or certain medications like contraceptives or hormone replacement therapy. Alternatively, it could also suggest that your body is producing more E1, the primary form of estrogen during menopause, which could be due to aging or early onset of menopause. It's important to note that this ratio is just one aspect of your hormonal health and doesn't provide a complete picture on its own.

Symptoms of low levels of E3/(E1+E2) could include irregular menstrual cycles, hot flashes, mood swings, or other symptoms typically associated with hormonal imbalances. However, it's also possible to have a low E3/(E1+E2) ratio without experiencing any noticeable symptoms.