Anti-Chromatin

Chromatin Antibody

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What's

Anti-Chromatin

Anti-Chromatin, also known as Chromatin Antibody, is a special kind of protein made by your body's defense system. Usually, your immune system protects you from harmful things like germs. But sometimes, it can accidentally attack your own cells, creating these proteins called autoantibodies. Anti-Chromatin specifically goes after chromatin, a substance in the center of your cells that helps pack DNA into a smaller space so it can fit inside the cell. Chromatin is really important for cell growth, division, and fixing any damage. In short, Anti-Chromatin is a sign that your immune system is acting a bit unusual, giving a clue about what's going on inside your body's defense system.

If Your Levels Are High

High levels of Anti-Chromatin might mean that your immune system is working harder than usual. This could be due to various reasons, such as fighting off an infection, reacting to certain medications like blood pressure drugs or antibiotics, or even dealing with stress. It's also possible that your body's defense system is accidentally attacking its own cells, which can happen in conditions like lupus and rheumatoid arthritis. Keep in mind that high Anti-Chromatin levels are just one part of the bigger picture, and other factors should be considered to fully understand your health situation.

Symptoms of High Levels

Symptoms of high levels of Anti-Chromatin could include fatigue, joint pain, skin rashes, and unexplained fever.

If Your Levels are Low

Low levels of Anti-Chromatin might mean that your body isn't making as many of these autoantibodies as it usually does. This could be due to various reasons, such as how your body reacts to certain medications like corticosteroids or immunosuppressants, a temporary decrease in your immune system's activity, or it might just be a sign of your overall health. It's also possible that your body is doing a good job at controlling its immune response, which keeps the production of these autoantibodies in check. Keep in mind that Anti-Chromatin levels can change over time and may not always give a full picture of what's happening with your immune system.

Symptoms of Low Levels

Symptoms of low levels of Anti-Chromatin are typically not noticeable, as this condition often doesn't present with specific symptoms.

See References

Test for

Chromatin Antibody

AutoImmune Analyzer

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Serum

This test measures antinuclear antibodies and other related markers to help diagnose autoimmune disease. Antinuclear antibodies are present in systemic lupus erythematosus, Sjogren’s Syndrome, scleroderma, mixed connective tissue disease, drug-induced lupus, and rheumatoid arthritis.

ANA Screen + 11 ANA Components

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Serum

The ANA Screen detects the presence of clinically relevant circulating autoantibodies in serum. Antinuclear antibodies are present in systemic lupus erythematosus, Sjogren’s Syndrome, scleroderma, mixed connective tissue disease, drug induced lupus, and rheumatoid arthritis.

ANA 11 Components (no ANA Screen)

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Serum

This test measures 11 antinuclear antibodies to help diagnose autoimmune disease. Antinuclear antibodies are present in systemic lupus erythematosus, Sjogren’s Syndrome, scleroderma, mixed connective tissue disease, drug-induced lupus, and rheumatoid arthritis.

Chromatin

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Serum

This is a single-marker test measuring antibodies to chromatin. More than 50% of patients with SLE (systemic lupus erythematosus) exhibit reactivity with chromatin.

CONTENTS

What is it?

High Levels

Low Levels

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