Anti-EBNA IgG

EBV Nuclear Antigen Antibody IgG

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What's

Anti-EBNA IgG

Anti-EBNA IgG, or Epstein-Barr Virus Nuclear Antigen Antibody IgG, is a special kind of defense protein that your body makes when it has been infected with the Epstein-Barr virus (EBV). This virus is often responsible for causing infectious mononucleosis, also known as "mono." When Anti-EBNA IgG is found in your blood, it means that your body has come across EBV at some point in the past. Think of it as a historical sign, showing that your body has successfully fought off this specific virus before. This defense protein stays in your system for a long time, helping to protect you from getting infected with EBV again in the future.

If Your Levels Are High

Elevated levels of Anti-EBNA IgG might mean that your body is actively fighting the Epstein-Barr virus (EBV), possibly due to a new infection or reawakening of an old one. Sometimes, stress, tiredness, or certain medications like steroids or immunosuppressants can cause the virus to become active again. It's also possible that your immune system is making more of these antibodies in response to another health issue, like an autoimmune condition, where the body mistakenly attacks its own tissues. So, high levels of Anti-EBNA IgG could be a sign of an EBV infection, reactivation, or an unrelated health problem.

Symptoms of High Levels

Symptoms of high levels of Anti-EBNA IgG could include fatigue, fever, sore throat, swollen lymph nodes, and a general feeling of being unwell. However, it's also possible to have elevated levels of this antibody without experiencing any noticeable symptoms.

If Your Levels are Low

Low levels of Anti-EBNA IgG might mean that your body hasn't come across the Epstein-Barr virus (EBV) before, or it could be that your immune system didn't create enough of these defense proteins to be easily detected. This could happen if your immune system is weaker than usual, maybe due to certain medications like steroids or chemotherapy drugs, or if you have a health condition that affects your immune system. It's also possible that you've been recently infected with EBV, and your body just hasn't had enough time to make these long-lasting antibodies yet.

Symptoms of Low Levels

Symptoms of low levels of Anti-EBNA IgG are typically non-existent, as this test is more of an indicator of past exposure to the Epstein-Barr virus rather than a measure of current health or disease status.

See References

Test for

EBV Nuclear Antigen Antibody IgG

Epstein-Barr Evaluation

Access Med Labs

Serum

The Epstein-Barr Evaluation assesses several antibodies to the Epstein-Barr virus (EBV). It is performed to confirm active, past, or indeterminate infection for EBV-associated infectious mononucleosis.

Epstein-Barr Virus (EBV) Panel

Immunosciences Lab, Inc.

Serum

EBV contributes to more than 30 autoimmune disorders. Detection of IgG or IgM antibodies to various EBV antigens indicates either past infection, primary reactivation, or re-infection with Epstein-Barr Virus or Herpes Type 4.

Epstein-Barr Nuclear Ag, IgG

Access Med Labs

Serum

This is a single-marker test measuring IgG antibody response to EBV nuclear antigen.

Long COVID Panel

Immunosciences Lab, Inc.

Serum

The Long COVID Panel is used to detect three major viruses (EBV, HHV-6, and SARS-CoV-2) associated with long COVID and autoimmunity. It has been found that increased levels of antibodies against EBV and HHV-6 correlate with the severity of long COVID.

Viral Panel Premier

Immunosciences Lab, Inc.

Serum

This panel measures antibodies against six different viruses (EBV, CMV, HSV-1, HSV-2, HHV-6, VZV) that are involved in different inflammatory autoimmune diseases, chronic fatigue syndrome or myalgic encephalitis, neurodegenerative disorders such as Alzheimer’s and Parkinson’s, and neurological disorders such as Guillain-Barré syndrome and multiple sclerosis. Reactivation of these viruses is a major driver in increasing the severity of symptoms in patients with COVID-19. The test confirms immunological memory against Varicella zoster (VZV), the causative agent for shingles.

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